Search on: RECEPTOR, TIE-2 
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Descriptor English:   Receptor, TIE-2 
Descriptor Spanish:   Receptor TIE-2 
Descriptor Portuguese:   Receptor TIE-2 
Synonyms English:   Angiopoietin Receptor Tie-2
TIE-2-RTK
TIE2 Tyrosine Kinase
Tek Receptor
Tie2 Receptor
Angiopoietin Receptor Tie 2
Receptor Tie-2, Angiopoietin
Receptor, TIE 2
Receptor, Tek
Receptor, Tie2
TIE 2 Receptor Tyrosine Kinase
TIE-2 Receptor
Tie-2, Angiopoietin Receptor
Tyrosine Kinase, TIE2
TIE-2 Receptor Tyrosine Kinase  
Tree Number:   D08.811.913.696.620.682.725.400.925.500
D12.776.543.750.630.687.500
Definition English:   A TIE receptor tyrosine kinase that is found almost exclusively on ENDOTHELIAL CELLS. It is required for both normal embryonic vascular development (NEOVASCULARIZATION, PHYSIOLOGIC) and tumor angiogenesis (NEOVASCULARIZATION, PATHOLOGIC). 
Indexing Annotation English:   see SCR for organism-specific terms
History Note English:   2004; use RECEPTOR TIE-2 (NM) 1993-2003 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   38229 
Unique Identifier:   D042787 

Occurrence in VHL:
 

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